1
general::
Phrase(s): no matter how you slice it
Fig. no matter what your perspective is; no matter how you try to portray something. • No matter how you slice it, the results of the meeting present all sorts of problems for the office staff.
McGrawhill's American Idioms And Phrasal Verbs
2
general::
Regardless of how one views something, as in No matter how you slice it, he's still guilty of perjury. This expression uses slice in the sense of "cut apart." [Colloquial; first half of 1900s]
American Heritage Idioms